Non-GMP Manufacturing/ Pilot Scale
At CRAMSN Research Park, we enable efficient technology transfer from laboratory-scale research to commercial manufacturing using miniature glass cylindrical reactors for precise process development. Our approach accelerates the preclinical development of New Chemical Entities (NCEs) by providing a customized, rapid, and scalable solution tailored to client needs.
Our Value Proposition
Discovery Research
-
Quick access to building blocks and key intermediates to support early-stage innovation
-
Efficient synthesis strategies that prioritize time-sensitive discovery
-
Scalable supply of compounds from 100g to a few kilos for research needs
Early-Phase Development
-
Rapid availability of drug substance for toxicology studies
-
Phase-appropriate process research & development (PRD) to facilitate smooth scale-up for clinical trials
With a strong focus on speed, precision, and compliance, CRAMSN ensures a seamless transition from discovery to development, enabling faster market readiness for breakthrough therapeutics.
Infrastructure
-
Extensive Lab Infrastructure: 350+ fume hoods and R&D labs equipped with cylindrical reactors (250mL to 5L).
-
Kilo Lab Capabilities: Cylindrical reactors ranging from 10L to 100L for scale-up studies.
-
High-Pressure Processing: 6kL autoclave with 5-10 kg/cm² design pressure.
-
Downstream Processing: Includes Pressure Nutsche filter, vacuum tray dryer, and 20L rotavapor.
-
Temperature Control: Huber unit enables operations from -78°C to 180°C.
-
Specialized Facilities: Dedicated steroid and potent manufacturing units.
Chemistry Capabilities
Expertise in
-
Metal promoted cross coupling reaction
-
Halogenation reactions
-
High pressure hydrogenation
-
Metal hydrate reactions
-
Carbohydrates
-
Lipids
-
Peptides
-
PEGylation
-
Asymmetric synthesis
-
Deuterated compound
-
Heterocyclic chemistry
-
Asymmetric hydrogenation
-
Chiral synthesis
-
Steroids & HORMONAL Compounds
-
Oncology Products
Why CRAMSN Non-GMP Pilot Development Facility?
>
Quick turnaround of sample delivery
>
A strong scientific and analytica team
>
Infrastructure for mg to kg synthesis
>
Large network of qualified strategic business partners