Non-GMP Manufacturing/ Pilot Scale

At CRAMSN Research Park, we enable efficient technology transfer from laboratory-scale research to commercial manufacturing using miniature glass cylindrical reactors for precise process development. Our approach accelerates the preclinical development of New Chemical Entities (NCEs) by providing a customized, rapid, and scalable solution tailored to client needs.

Our Value Proposition

Discovery Research
  • Quick access to building blocks and key intermediates to support early-stage innovation

  • Efficient synthesis strategies that prioritize time-sensitive discovery

  • Scalable supply of compounds from 100g to a few kilos for research needs

Early-Phase Development
  • Rapid availability of drug substance for toxicology studies

  • Phase-appropriate process research & development (PRD) to facilitate smooth scale-up for clinical trials

With a strong focus on speed, precision, and compliance, CRAMSN ensures a seamless transition from discovery to development, enabling faster market readiness for breakthrough therapeutics.

Infrastructure
  • Extensive Lab Infrastructure: 350+ fume hoods and R&D labs equipped with cylindrical reactors (250mL to 5L).

  • Kilo Lab Capabilities: Cylindrical reactors ranging from 10L to 100L for scale-up studies.

  • High-Pressure Processing: 6kL autoclave with 5-10 kg/cm² design pressure.

  • Downstream Processing: Includes Pressure Nutsche filter, vacuum tray dryer, and 20L rotavapor.

  • Temperature Control: Huber unit enables operations from -78°C to 180°C.

  • Specialized Facilities: Dedicated steroid and potent manufacturing units.

Chemistry Capabilities

Expertise in

  • Metal promoted cross coupling reaction

  • Halogenation reactions

  • High pressure hydrogenation

  • Metal hydrate reactions

  • Carbohydrates

  • Lipids

  • Peptides

  • PEGylation

  • Asymmetric synthesis

  • Deuterated compound

  • Heterocyclic chemistry

  • Asymmetric hydrogenation

  • Chiral synthesis

  • Steroids & HORMONAL Compounds

  • Oncology Products

Why CRAMSN Non-GMP Pilot Development Facility?

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Quick turnaround of sample delivery

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A strong scientific and analytica team

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Infrastructure for mg to kg synthesis

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Large network of qualified strategic business partners

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